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Article

Functional impacts of non-synonymous single nucleotide polymorphisms: selective constraint and structural environments.

FEBS letters - 20 Feb 2006

Bao Lei, Cui Yan

Abstract excerpt

In this work, we studied the correlations between selective constraint, structural environments and functional impacts of non-synonymous single nucleotide polymorphisms (nsSNPs). We found that the relation between solvent accessibility and functional impacts of nsSNPs is not as simple as generally thought. Finer structural classifications need to be taken into account to reveal the complex relations between the...

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PMID: 16442527
DOI: 10.1016/j.febslet.2006.01.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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