Article
Computational approaches and resources in single amino acid substitutions analysis toward clinical research.
Advances in protein chemistry and structural biology - 1 Jan 2014
George Priya Doss C, Chakraborty Chiranjib, Narayan Vaishnavi, Thirumal Kumar D
Abstract excerpt
Single amino acid substitutions (SAPs) belong to a class of SNPs in the coding region, which alter the protein function during the translation process. Storage of more information regarding SAPs in public databases will soon become a major hurdle in characterizing the functional SAPs. In such a demanding era, biology has to rely on bioinformatics, which can work its way through to solve the problems at hand by...
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