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Computational approaches and resources in single amino acid substitutions analysis toward clinical research.

Advances in protein chemistry and structural biology - 1 Jan 2014

George Priya Doss C, Chakraborty Chiranjib, Narayan Vaishnavi, Thirumal Kumar D

Abstract excerpt

Single amino acid substitutions (SAPs) belong to a class of SNPs in the coding region, which alter the protein function during the translation process. Storage of more information regarding SAPs in public databases will soon become a major hurdle in characterizing the functional SAPs. In such a demanding era, biology has to rely on bioinformatics, which can work its way through to solve the problems at hand by...

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PMID: 24629192
DOI: 10.1016/B978-0-12-800168-4.00010-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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