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Article

Predicting disease-associated substitution of a single amino acid by analyzing residue interactions.

BMC bioinformatics - 12 Jan 2011

Li Yizhou, Wen Zhining, Xiao Jiamin, Yin Hui, Yu Lezheng, Yang Li, Li Menglong

Abstract excerpt

BACKGROUND: The rapid accumulation of data on non-synonymous single nucleotide polymorphisms (nsSNPs, also called SAPs) should allow us to further our understanding of the underlying disease-associated mechanisms. Here, we use complex networks to study the role of an amino acid in both local and...

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PMID: 21223604
DOI: 10.1186/1471-2105-12-14
PMCID: PMC3027113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21223604-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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