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Article

Human immunodeficiency virus type 1 env evolves toward ancestral states upon transmission to a new host.

Journal of virology - 1 Feb 2006

Herbeck Joshua T, Nickle David C, Learn Gerald H, Gottlieb Geoffrey S, Curlin Marcel E, Heath Laura, Mullins James I

Abstract excerpt

Selecting human immunodeficiency virus (HIV) sequences for inclusion within vaccines has been a difficult problem, as circulating HIV strains evolve relentlessly and become increasingly divergent over time. We report an assessment of this divergence from three perspectives: (i) across different hosts as a function of time of infection, (ii) between donors and recipients in known transmission pairs, and (iii)...

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Topics

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Share to Evolution, Molecular
Share to Gene Products, env

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, env

Share to Genome, Viral

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Share to Sequence Analysis, DNA

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Source

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Identifiers

PMID: 16439520
DOI: 10.1128/JVI.80.4.1637-1644.2006
PMCID: PMC1367147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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