Article
In vitro and in vivo antibacterial activities of DK-507k, a novel fluoroquinolone.
Antimicrobial agents and chemotherapy - 1 Dec 2003
Otani Tsuyoshi, Tanaka Mayumi, Ito Emi, Kurosaka Yuichi, Murakami Yoichi, Onodera Kiyomi, Akasaka Takaaki, Sato Kenichi
Abstract excerpt
The antibacterial activities of DK-507k, a novel quinolone, were compared with those of other quinolones: ciprofloxacin, gatifloxacin, levofloxacin, moxifloxacin, sitafloxacin, and garenoxacin (BMS284756). DK-507k was as active as sitafloxacin and was as active as or up to eightfold more active than gatifloxacin, moxifloxacin, and garenoxacin against Streptococcus pneumoniae, methicillin-susceptible and...
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