Article
Activity of BMS-284756, a novel des-fluoro(6) quinolone, against Staphylococcus aureus, including contributions of mutations to quinolone resistance.
Antimicrobial agents and chemotherapy - 1 Apr 2002
Low D E, Muller M, Duncan C L, Willey B M, de Azavedo J C, McGeer A, Kreiswirth B N, Pong-Porter S, Bast D J
Abstract excerpt
The in vitro activity of BMS-284756 against 602 Staphylococcus aureus isolates, including 152 that were both methicillin and ciprofloxacin resistant (MIC > or = 4 microg/ml), was determined. For ciprofloxacin-susceptible and nonsusceptible isolates, the MICs at which 50% of organisms were inhibited were 0.015 and 2 microg/ml and the MICs at which 90% of organisms were inhibited were 0.03 and 4 microg/ml,...
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