Article
Antistaphylococcal activity of DX-619, a new des-F(6)-quinolone, compared to those of other agents.
Antimicrobial agents and chemotherapy - 1 Aug 2005
Bogdanovich Tatiana, Esel Duygu, Kelly Linda M, Bozdogan Bülent, Credito Kim, Lin Gengrong, Smith Kathy, Ednie Lois M, Hoellman Dianne B, Appelbaum Peter C
Abstract excerpt
The in vitro activity of DX-619, a new des-F(6)-quinolone, was tested against staphylococci and compared to those of other antimicrobials. DX-619 had the lowest MIC ranges/MIC(50)s/MIC(90)s (microg/ml) against 131 Staphylococcus aureus strains (</=0.002 to 2.0/0.06/0.5) and 128 coagulase-negative staphylococci (0.004 to 0.25/0.016/0.125). Among strains tested, 76 S. aureus strains and 51 coagulase-negative...
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