Article
Endothelial nitric oxide synthase haplotypes affect the susceptibility to hypertension in patients with type 2 diabetes mellitus.
Atherosclerosis - 1 Nov 2006
Sandrim Valéria C, de Syllos Roger W C, Lisboa Hugo R K, Tres Glaucia S, Tanus-Santos Jose E
Abstract excerpt
Type 2 diabetes mellitus (T2DM) and hypertension (HT) commonly coexist. While endothelial nitric oxide synthase (eNOS) haplotypes have been associated with HT, it is unknown whether eNOS genotypes/haplotypes are associated with altered susceptibility to HT in patients with T2DM. We studied the distribution of three eNOS genetic polymorphisms: a single nucleotide polymorphism in the promoter region (T(-786)C), in...
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