Article
eNOS haplotype associated with hypertension in obese children and adolescents.
International journal of obesity (2005) - 1 Mar 2011
Souza-Costa D C, Belo V A, Silva P S, Sertorio Jonas T, Metzger I F, Lanna C M, Machado M A, Tanus-Santos J E
Abstract excerpt
OBJECTIVE: The aim of our study is to investigate whether genetic polymorphisms in the endothelial nitric oxide synthase (eNOS) gene (in the promoter region T(-786)C, in exon 7 (Glu298Asp) and in intron 4 (4b/4a)) or eNOS haplotypes are associated with hypertension in obese children and adolescents. METHODS: We genotyped 175 healthy (controls), 110 normotensive obese and 73 hypertensive obese children and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
