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Article

Endothelial nitric oxide synthase haplotypes are related to blood pressure elevation, but not to resistance to antihypertensive drug therapy.

Journal of hypertension - 1 Dec 2006

Sandrim Valéria C, Yugar-Toledo Juan C, Desta Zeruesenay, Flockhart David A, Moreno Heitor, Tanus-Santos Jose E

Abstract excerpt

OBJECTIVES: Most hypertensive patients require two or more drugs to control arterial blood pressure effectively. Although endothelial nitric oxide synthase (eNOS) haplotypes have been associated with hypertension, it is unknown whether eNOS genotypes/haplotypes are associated with resistance to antihypertensive therapy. METHODS: We studied the distribution of three eNOS genetic polymorphisms: single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hormonal Regulation and Hypertension

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Share to Nitric Oxide and Endothelin Effects

Share to Nitric Oxide Synthase Type III

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 17082721
DOI: 10.1097/01.hjh.0000251899.47626.4f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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