Article
eNOS tag SNP haplotypes in hypertensive disorders of pregnancy.
DNA and cell biology - 1 Dec 2012
Muniz Ludmila, Luizon Marcelo R, Palei Ana C T, Lacchini Riccardo, Duarte Geraldo, Cavalli Ricardo C, Tanus-Santos Jose E, Sandrim Valeria C
Abstract excerpt
Haplotypes formed by polymorphisms (T-786C, rs2070744; a variable number of tandem repeats in intron 4, and Glu298Asp, rs1799983) of the eNOS gene were associated previously with gestational hypertension (GH) and preeclampsia (PE). However, no study has explored the Tag SNPs rs743506 and rs7830 in these disorders. The aim of the current study was to compare the distribution of the genotypes and haplotypes formed...
Read the complete abstract on PubMed