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Article

Association between the dopamine D2 receptor TaqI A2 allele and low activity COMT allele with obsessive-compulsive disorder in males.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Aug 2006

Denys Damiaan, Van Nieuwerburgh Filip, Deforce Dieter, Westenberg Herman

Abstract excerpt

BACKGROUND: Mounting evidence suggests the involvement of the dopamine system in the pathophysiology of obsessive-compulsive disorder. METHOD: The relationship of the dopamine D(2) receptor (DRD2) TaqI A, and catechol-O-methyl-transferase (COMT) NlaIII High/Low activity polymorphism to obsessive-compulsive disorder (OCD) was examined in a sample of 150 patients and 150 controls. RESULTS: OCD patients did not show...

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Source

Identifiers

PMID: 16427255
DOI: 10.1016/j.euroneuro.2005.12.001

Genes

DRD2
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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