Article
Sexually dimorphic relationship of a 5-HT2A promoter polymorphism with obsessive-compulsive disorder.
Biological psychiatry - 15 Feb 2001
Enoch M A, Greenberg B D, Murphy D L, Goldman D
Abstract excerpt
BACKGROUND: In an earlier analysis of 73 subjects from this study, the reduced activity catechol O-methyltransferase variant was shown to be associated with obsessive-compulsive disorder in men only. We hypothesized that the 5-HT2A promoter polymorphism, -1438G>A, previously associated with anorexia nervosa, would be more abundant in women with obsessive-compulsive disorder. METHODS: One hundred and one Caucasian...
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