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Article

Brain 5-HT synthesis in the Flinders Sensitive Line rat model of depression: an autoradiographic study.

Neurochemistry international - 1 Apr 2006

Hasegawa Shu, Nishi Kyoko, Watanabe Arata, Overstreet David H, Diksic Mirko

Abstract excerpt

Alterations of serotonin (5-HT) levels and serotonergic transmission have been associated with depression. 5-HT synthesis is an important factor of serotonergic neurotransmission that may also be altered in depression. Many studies of the relationships between brain serotonergic functions and affective disorders have been performed in different animal models. In this study, brain regional 5-HT synthesis was...

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Identifiers

PMID: 16427159
DOI: 10.1016/j.neuint.2005.11.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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