Article
Both acute and chronic buspirone treatments have different effects on regional 5-HT synthesis in Flinders Sensitive Line rats (a rat model of depression) than in control rats.
Neurochemistry international - 1 Jan 2000
Nishi Kyoko, Kanemaru Kazuya, Hasegawa Shu, Watanabe Arata, Diksic Mirko
Abstract excerpt
The main objective of this investigation was to evaluate the effects of buspirone, a 5-HT(1A) agonist with some partial agonist properties and also an antidepressant, on regional 5-HT synthesis in Flinders Sensitive Line (FSL) rats ("depressed"), and to compare the effects to the Flinders Resista...
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