Article
Non-HLA autoimmunity genetic factors contributing to Autoimmune Polyglandular Syndrome type II in Tunisian patients.
Human immunology - 1 Jul 2012
Fourati Hajer, Bouzid Dorra, Abida Olfa, Kharrat Najla, Mnif Fatma, Haddouk Samy, Fesel Constantin, Costa João, Ben Ayed Mourad, Abid Mohamed, Rebai Ahmed, Penha-Gonçalves Carlos, Masmoudi Hatem
Abstract excerpt
Autoimmune Polyglandular Syndrome Type II (APSII) is characterized by the co-occurrence of clinical insufficiency of at least two endocrine glands. Although, HLA determinants of APSII predisposition have been identified, little attention has been paid to non-HLA genes. Here, we used SNP genotyping in a Sequenom platform and genetic association tests to study a cohort of 60 APSII Tunisian patients presenting...
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