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Article

Association of Interleukin-1B and Interleukin-4 Gene Variants with Autoimmune Thyroid Diseases in Tunisian Population.

Immunological investigations - 1 May 2016

Zaaber Ines, Mestiri Souhir, Hammedi Hounayda, Marmouch Hela, Mahjoub Silvia, Tensaout Besma Bel Hadj Jrad, Said Khaled

Abstract excerpt

Autoimmune thyroid diseases (AITD) including Graves' disease (GD) and Hashimoto's thyroiditis (HT) are complex genetic diseases. Cytokines IL-1B and IL-4 play a role in the pathogenesis of AITD. This study was conducted on Tunisian patients with GD or HT to investigate the association of IL-1B and IL-4 gene polymorphisms with the risk and the prognosis of AITD. A total of 358 healthy controls and 341 patients...

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PMID: 27100882
DOI: 10.3109/08820139.2016.1153650

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TPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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