Article
Structural stability and chromosome-specific telomere length is governed by cis-acting determinants in humans.
Human molecular genetics - 1 Mar 2006
Britt-Compton Bethan, Rowson Jan, Locke Matthew, Mackenzie Ian, Kipling David, Baird Duncan M
Abstract excerpt
Single telomere length analysis (STELA) of the XpYp telomere has revealed extensive allelic variation and ultra-short telomeres in senescent cells. Superimposed on end-replication losses are additional mutational events that result in large-scale changes in telomere length. In order to establish if the dynamics of the XpYp telomere are typical of human telomeres, here we describe an analysis using STELA of the...
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