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Article

Mechanisms underlying telomere repeat turnover, revealed by hypervariable variant repeat distribution patterns in the human Xp/Yp telomere.

The EMBO journal - 1 Nov 1995

Baird D M, Jeffreys A J, Royle N J

Abstract excerpt

Sequences immediately adjacent to the human Xp/Yp telomere exhibit a high frequency of base substitutional polymorphisms, together with almost complete linkage disequilibrium, to create only a few diverged haplotypes. This sequence divergence has been used to develop a PCR-based system for mapping the distribution of the telomere (TTAGGG) and variant repeats (TGAGGG and TCAGGG) at the proximal end of the telomere...

Topics

Alleles
Base Sequence
Chromosome Mapping
DNA
Haplotypes
Humans
Minisatellite Repeats
Molecular Sequence Data
Polymorphism, Single-Stranded Conformational
Sequence Analysis
Telomere

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

X Chromosome

Y Chromosome

Source

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Identifiers

PMID: 7489732
DOI: 10.1002/j.1460-2075.1995.tb00227.x
PMCID: PMC394652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7489732-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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