Article
Short telomeres are preferentially elongated by telomerase in human cells.
FEBS letters - 17 Sept 2009
Britt-Compton Bethan, Capper Rebecca, Rowson Jan, Baird Duncan M
Abstract excerpt
Short telomeres have been shown to be preferentially elongated in both yeast and mouse models. We examined this in human cells, by utilising cells with large allelic telomere length differentials and observing the relative rates of elongation following the expression of hTERT. We observed that short telomeres are gradually elongated in the first 26 PDs of growth, whereas the longer telomeres displayed limited...
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