Article
Telomere dynamics in human cells.
Biochimie - 1 Jan 2008
Baird Duncan M
Abstract excerpt
Human telomeres are intrinsically dynamic structures, with multiple biological processes operating to generate substantial length heterogeneity. Processes that operate specifically at the terminus, that include the end-replication problem coupled with C-strand resection, result in gradual telomere erosion with ongoing cell division. Rates of telomere erosion can be modulated by cell culture conditions and...
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