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Article

Extensive allelic variation and ultrashort telomeres in senescent human cells.

Nature genetics - 1 Feb 2003

Baird Duncan M, Rowson Jan, Wynford-Thomas David, Kipling David

Abstract excerpt

By imposing a limit on the proliferative lifespan of most somatic cells, telomere erosion represents an innate mechanism for tumor suppression and may contribute to age-related disease. A detailed understanding of the pathways that link shortened telomeres to replicative senescence has been severely hindered by the inability of current methods to analyze telomere dynamics in detail. Here we describe single...

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PMID: 12539050
DOI: 10.1038/ng1084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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