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Article

Small eye phenotypes observed in a human tau gene transgenic rat.

Current eye research - 1 Jan 2006

Goto Kazuo, Yasuda Masahiko, Sugawara Ayako, Kuramochi Takashi, Itoh Toshio, Azuma Noriyuki, Ito Mamoru

Abstract excerpt

We developed a rat line showing small eye from transgenic rats that were obtained by microinjection of a DNA segment containing the human (h)tau cDNA (GenBank: BC000558: 31-677,774-1180) expressed under control of CAG promoter, which is related to Alzheimer disease, into the pronuclei rat embryos. The rat line was established by selective brother-sister mating of rats showing small eyes. Of 11 offspring in the...

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Identifiers

PMID: 16421024
DOI: 10.1080/02713680500478675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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