Article
Selective delivery of secretory cargo in Golgi-derived carriers of nonepithelial cells.
Traffic (Copenhagen, Denmark) - 1 Apr 2002
Rustom Amin, Bajohrs Mark, Kaether Christoph, Keller Patrick, Toomre Derek, Corbeil Denis, Gerdes Hans-Hermann
Abstract excerpt
In epithelial cells, soluble cargo proteins destined for basolateral or apical secretion are packaged into distinct trans-Golgi network-derived transport carriers. Similar carriers, termed basolateral- and apical-like, have been observed in nonepithelial cells using ectopically expressed membrane marker proteins. Whether these cells are capable of selectively packaging secretory proteins into distinct carriers is...
Read the complete abstract on PubMedTopics
- Animals
- Bacterial Proteins
- Biological Transport
- Cell Line
- Chlorocebus aethiops
- Chromogranins