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Article

The H,K-ATPase beta subunit as a model to study the role of N-glycosylation in membrane trafficking and apical sorting.

The Journal of biological chemistry - 10 Sept 2004

Vagin Olga, Turdikulova Shahlo, Sachs George

Abstract excerpt

The role of N-glycosylation in trafficking of an apical membrane protein, the gastric H,K-ATPase beta subunit linked to yellow fluorescent protein, was analyzed in polarized LLC-PK1 cells by confocal microscopy and surface-specific biotinylation. Deletion of the N-glycosylation sites at N1, N3, N5, and N7 but not at N2, N4, and N6 significantly slowed endoplasmic reticulum-to-Golgi trafficking, impaired apical...

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Identifiers

PMID: 15247221
DOI: 10.1074/jbc.M405453200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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