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Article

The role of the tnv protein and tnv RNA splicing signals in replication of HIV-1 IIIB isolates.

Virology - 1 Aug 1992

Göttlinger H G, Dorfman T, Cohen E A, Haseltine W A

Abstract excerpt

The requirement for tnv, a tat-env-rev fusion protein expressed by the IIIB strain of HIV-1, was tested. The expression of tnv was prevented by altering the 5' splice site that flanks the central coding exon of tnv. Mutants that carry such an altered 5' splice site replicate normally in an established T-cell line and in peripheral blood lymphocytes, demonstrating that tnv has no effect on virus replication....

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Source

Identifiers

PMID: 1641982
DOI: 10.1016/0042-6822(92)90585-d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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