Article
The role of the tnv protein and tnv RNA splicing signals in replication of HIV-1 IIIB isolates.
Virology - 1 Aug 1992
Göttlinger H G, Dorfman T, Cohen E A, Haseltine W A
Abstract excerpt
The requirement for tnv, a tat-env-rev fusion protein expressed by the IIIB strain of HIV-1, was tested. The expression of tnv was prevented by altering the 5' splice site that flanks the central coding exon of tnv. Mutants that carry such an altered 5' splice site replicate normally in an establ...
Topics
- Base Sequence
- Gene Products, env
- Gene Products, rev
- Gene Products, tat
- HIV-1
- Molecular Sequence Data
- Mutation
- RNA Splicing
- RNA, Viral
- Trans-Activators
- Viral Fusion Proteins
- rev Gene Products, Human Immunodeficiency Virus
- tat Gene Products, Human Immunodeficiency Virus