Article
The tat/rev intron of human immunodeficiency virus type 1 is inefficiently spliced because of suboptimal signals in the 3' splice site.
Journal of virology - 1 May 1994
Staffa A, Cochrane A
Abstract excerpt
Proportional expression of retroviral genes requires that splicing of the viral primary transcript be an inefficient process. Much of our current knowledge about retroviral suboptimal splicing comes from studies with Rous sarcoma virus. In this report, we describe the use of chimeric introns comp...
Topics
- Base Sequence
- DNA Mutational Analysis
- Genes, rev
- Genes, tat
- Globins
- HIV-1
- Introns
- Molecular Sequence Data
- Mutation
- RNA
- RNA Splicing
- Regulatory Sequences, Nucleic Acid
- Sequence Deletion