Article
HIV-1-specific CD4+ T cell responses in chronically HIV-1 infected blippers on antiretroviral therapy in relation to viral replication following treatment interruption.
Journal of clinical immunology - 1 Jan 2006
Papasavvas Emmanouil, Kostman Jay R, Thiel Brian, Pistilli Maxwell, Mackiewicz Agnieszka, Foulkes Andrea, Gross Robert, Jordan Kimberly A, Nixon Douglas F, Grant Robert, Poulin Jean-Francois, McCune Joseph M, Mounzer Karam, Montaner Luis J
Abstract excerpt
The impact of transient viral load blips on anti-HIV-1 immune responses and on HIV-1 rebound following treatment interruption (TI) is not known. Clinical and immunological parameters were measured during 40 weeks of antiretroviral therapy (ART) and following TI in an observational cohort of 16 chronically HIV-1-infected subjects with or without observed viral load blips during ART. During therapy, blips in seven...
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