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Multiple Treatment Interruptions and Protecting HIV-Specific CD4 T-Cells Enables Durable CTL Response and Viral Control

2023-10-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> The cell and gene therapy product AGT103-T was evaluated ( NCT04561258 ) for safety, immunogenicity, and persistence for up to 180 days post infusion. We sought to investigate the impact following analytical treatment interruptions (ATIs). <h4>METHODS</h4> Six patients suspended their antiretroviral therapy (ART) until their viral load reached 100,000 copies/mL in two successi...

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Literature Corpus work
4351efa5-1f53-5bdc-8f35-8b9e943b110c
DOI
10.1101/2023.10.24.23297421
Open publication

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Multiple Treatment Interruptions and Protecting HIV-Specific CD4 T-Cells Enables Durable CTL Response and Viral ControlDOI 10.1101/2023.10.24.23297421
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