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Article

Caspase recruitment domain protein 6 is a microtubule-interacting protein that positively modulates NF-kappaB activation.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jan 2006

Dufner Almut, Pownall Scott, Mak Tak W

Abstract excerpt

Proteins containing a caspase recruitment domain (CARD) play pivotal roles in signal transduction leading to apoptosis and NF-kappaB activation and inflammation. Here we identify and characterize human and mouse CARD protein 6 (CARD6), CARD-containing proteins of unique structure. CARD6 associates with microtubules and interacts with receptor-interacting protein (RIP)-like interacting caspase-like apoptosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 16418290
DOI: 10.1073/pnas.0510380103
PMCID: PMC1327733

Genes

CARD6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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