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Article

CARD6 is interferon inducible but not involved in nucleotide-binding oligomerization domain protein signaling leading to NF-kappaB activation.

Molecular and cellular biology - 1 Mar 2008

Dufner Almut, Duncan Gordon S, Wakeham Andrew, Elford Alisha R, Hall Håkan T, Ohashi Pamela S, Mak Tak W

Abstract excerpt

We have previously reported the cloning and characterization of CARD6, a caspase recruitment domain (CARD)-containing protein that is structurally related to the interferon (IFN)-inducible GTPases. CARD6 associates with microtubules and with receptor-interacting protein 2 (RIP2). RIP2 mediates NF-kappaB activation induced by the intracellular nucleotide-binding oligomerization domain (NOD) receptors that sense...

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Identifiers

PMID: 18160713
DOI: 10.1128/MCB.01359-07
PMCID: PMC2258768

Genes

CARD6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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