Article
Over-expression of S. cerevisiae G1 cyclins restores the viability of alg1 N-glycosylation mutants.
Current genetics - 1 Jan 1996
Benton B K, Plump S D, Roos J, Lennarz W J, Cross F R
Abstract excerpt
In budding yeast, one of three G1 cyclins is required for progression though START, when cells commit to a further round of cell division. We have identified mutations in ALG1 (ERC14), a gene required for N-glycosylation, which are inviable in a cln1 cln2 background but are rescued by over-expression of CLNs. CLN1 and CLN2 are much more efficient than CLN3 in rescuing the erc14-1 allele. The erc14-1 allele...
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