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Article

Lack of association between BRAF mutation and MAPK ERK activation in melanocytic nevi.

The Journal of investigative dermatology - 1 Jan 2006

Uribe Pablo, Andrade Leonardo, Gonzalez Sergio

Abstract excerpt

The mitogen-activated protein kinase (MAPK) extracellular signal-regulated kinase signaling pathway can be activated through mutations of V-RAF murine sarcoma viral oncogene homolog B1 (BRAF) oncogene, frequently found in melanoma (60%), common nevi (CN) (73-82%), and atypical nevi (AN) (52-80%)....

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Source

Identifiers

PMID: 16417232
DOI: 10.1038/sj.jid.5700011

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16417232-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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