Article
BRAF and NRAS mutations in melanoma and melanocytic nevi.
Melanoma research - 1 Aug 2006
Poynter Jenny N, Elder James T, Fullen Douglas R, Nair Rajan P, Soengas Maria S, Johnson Timothy M, Redman Bruce, Thomas Nancy E, Gruber Stephen B
Abstract excerpt
In this report, we investigated BRAF/NRAS mutations in samples from a case-control study of melanoma and a series of benign melanocytic nevi. We evaluated potential associations between BRAF mutations and histopathologic and pigmentary characteristics of melanoma. Mutations in BRAF and NRAS were detected by sequencing microdissected/laser-captured DNA from 18 in-situ melanomas, 64 primary melanomas, and 51 nevi....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.