Article
The Saccharomyces cerevisiae SPT7 gene encodes a very acidic protein important for transcription in vivo.
Genetics - 1 Feb 1995
Gansheroff L J, Dollard C, Tan P, Winston F
Abstract excerpt
Mutations in the SPT7 gene of Saccharomyces cerevisiae originally were identified as suppressors of Ty and delta insertion mutations in the 5' regions of the HIS4 and LYS2 genes. Other genes that have been identified in mutant hunts of this type have been shown to play a role in transcription. In this work we show that SPT7 is also important for proper transcription in vivo. We have cloned and sequenced the SPT7...
Topics
- Amino Acid Sequence
- Cell Nucleus
- Cloning, Molecular
- Genes, Fungal
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- RNA, Fungal
- RNA, Messenger
- Restriction Mapping
- Saccharomyces cerevisiae