Article
Analysis of transcriptional activation at a distance in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Aug 2007
Dobi Krista C, Winston Fred
Abstract excerpt
Most fundamental aspects of transcription are conserved among eukaryotes. One striking difference between yeast Saccharomyces cerevisiae and metazoans, however, is the distance over which transcriptional activation occurs. In S. cerevisiae, upstream activation sequences (UASs) are generally located within a few hundred base pairs of a target gene, while in Drosophila and mammals, enhancers are often several...
Topics
- Alcohol Dehydrogenase
- Blotting, Northern
- Chromatin
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Reporter
- Mutant Proteins
- Mutation
- Nucleic Acid Conformation
- Phenotype
- Saccharomyces cerevisiae