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Article

A gammaherpesvirus 68 gene 50 null mutant establishes long-term latency in the lung but fails to vaccinate against a wild-type virus challenge.

Journal of virology - 1 Feb 2006

Moser Janice M, Farrell Michael L, Krug Laurie T, Upton Jason W, Speck Samuel H

Abstract excerpt

The gammaherpesvirus immediate-early genes are critical regulators of virus replication and reactivation from latency. Rta, encoded by gene 50, serves as the major transactivator of the lytic program and is highly conserved among all the gammaherpesviruses, including Epstein-Barr virus, Kaposi's...

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Identifiers

PMID: 16415035
DOI: 10.1128/JVI.80.3.1592-1598.2006
PMCID: PMC1346930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16415035-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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