Article
A gammaherpesviral internal repeat contributes to latency amplification.
PloS one - 15 Aug 2007
Thakur Nagendra N, El-Gogo Susanne, Steer Beatrix, Freimüller Klaus, Waha Andreas, Adler Heiko
Abstract excerpt
BACKGROUND: Gammaherpesviruses cause important infections of humans, in particular in immunocompromised patients. The genomes of gammaherpesviruses contain variable numbers of internal repeats whose precise role for in vivo pathogenesis is not well understood. METHODOLOGY/PRINCIPAL FINDINGS: We used infection of laboratory mice with murine gammaherpesvirus 68 (MHV-68) to explore the biological role of the 40 bp...
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