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Article

Telomere length of normal leukocytes is affected by a functional polymorphism of hTERT.

Biochemical and biophysical research communications - 3 Mar 2006

Matsubara Yumiko, Murata Mitsuru, Yoshida Tadashi, Watanabe Kiyoaki, Saito Ikuo, Miyaki Koichi, Omae Kazuyuki, Ikeda Yasuo

Abstract excerpt

Transcriptional regulation of human telomerase reverse transcriptase (hTERT), a catalytic subunit of telomerase, is essential for telomerase activity associated with telomere length. In this study, we investigated the effects of a (-1327)T/C polymorphism within the hTERT promoter region on the hTERT promoter activity and leukocyte telomere length in normal individuals. The promoter activity in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16412982
DOI: 10.1016/j.bbrc.2005.12.163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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