Article
Coronary artery disease and a functional polymorphism of hTERT.
Biochemical and biophysical research communications - 22 Sept 2006
Matsubara Yumiko, Murata Mitsuru, Watanabe Kiyoaki, Saito Ikuo, Miyaki Koichi, Omae Kazuyuki, Ishikawa Mie, Matsushita Kenichi, Iwanaga Shiro, Ogawa Satoshi, Ikeda Yasuo
Abstract excerpt
Genetic variation, a -1327T/C polymorphism, of human telomerase reverse transcriptase (hTERT) is associated with leukocyte telomere length in healthy subjects, but clinical significances of this functional polymorphism are not clear. Recently, the relationship between the telomere system and coronary artery disease (CAD) was reported. We investigated the association between the -1327T/C polymorphism and (a)...
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