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The relationship between leukocyte telomere length and TERT, TRF1 single nucleotide polymorphisms in healthy people of different age groups.

Biogerontology - 1 Feb 2020

Gedvilaite Greta, Vilkeviciute Alvita, Kriauciuniene Loresa, Banevičius Mantas, Liutkeviciene Rasa

Abstract excerpt

Telomeres are nucleoprotein structures that cap the end of each chromosome and function to maintain genome stability. The length of telomeres is known to shorten with each cell division and it is well-established that telomere attrition is related to replicative capacity in vitro. Moreover, telomere loss is also correlated with the process of aging in vivo. That is why we aimed to find any associations of...

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PMID: 31646401
DOI: 10.1007/s10522-019-09843-0

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