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Article

Leukocyte telomere length and hTERT genetic polymorphism rs2735940 influence the renal cell carcinoma clinical outcome.

Future oncology (London, England) - 1 Jun 2020

Morais Mariana, Dias Francisca, Resende Telma, Nogueira Inês, Oliveira Jorge, Maurício Joaquina, Teixeira Ana L, Medeiros Rui

Abstract excerpt

Aim: Analysis of the genetic hTERT-1327 C>T (rs2735940) influence on leukocyte telomere length (LTL) and tumor development, progression and overall survival in renal cell carcinoma (RCC) patients. Materials & methods: Using leukocyte DNA of RCC patients and healthy individuals, LTL measurement and allelic discrimination of rs2735940 was performed by real-time PCR. Results: RCC patients showed shorter LTL than...

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PMID: 32422075
DOI: 10.2217/fon-2019-0795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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