Article
Rac function in epithelial tube morphogenesis.
Developmental biology - 15 Feb 2006
Pirraglia Carolyn, Jattani Rakhi, Myat Monn Monn
Abstract excerpt
Epithelial cell migration and morphogenesis require dynamic remodeling of the actin cytoskeleton and cell-cell adhesion complexes. Numerous studies in cell culture and in model organisms have demonstrated the small GTPase Rac to be a critical regulator of these processes; however, little is known about Rac function in the morphogenic movements that drive epithelial tube formation. Here, we use the embryonic...
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