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Article

Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons.

Genes & development - 1 Sept 2004

Lundström Annika, Gallio Marco, Englund Camilla, Steneberg Pär, Hemphälä Johanna, Aspenström Pontus, Keleman Krystyna, Falileeva Ludmilla, Dickson Barry J, Samakovlis Christos

Abstract excerpt

Slit proteins steer the migration of many cell types through their binding to Robo receptors, but how Robo controls cell motility is not clear. We describe the functional analysis of vilse, a Drosophila gene required for Robo repulsion in epithelial cells and axons. Vilse defines a conserved family of RhoGAPs (Rho GTPase-activating proteins), with representatives in flies and vertebrates. The phenotypes of vilse...

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Identifiers

PMID: 15342493
DOI: 10.1101/gad.310204
PMCID: PMC515293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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