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Article

The H2 MAPT haplotype is associated with familial frontotemporal dementia.

Neurobiology of disease - 1 May 2006

Ghidoni Roberta, Signorini Simona, Barbiero Laura, Sina Elena, Cominelli Paola, Villa Aldo, Benussi Luisa, Binetti Giuliano

Abstract excerpt

There is now considerable evidence that the gene encoding for tau protein (MAPT) is implicated in frontotemporal dementia (FTD). The role of MAPT haplotypes in neurodegenerative diseases has been suggested, but their contribution in familial dementia has not been extensively investigated. Here, we investigated (1) the association between the MAPT haplotypes and sporadic (sFTD) or familial FTD (FFTD) (controls n =...

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Source

Identifiers

PMID: 16410051
DOI: 10.1016/j.nbd.2005.11.013

Genes

MAPT
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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