Article
Association between tau H2 haplotype and age at onset in frontotemporal dementia.
Archives of neurology - 1 Sept 2005
Borroni Barbara, Yancopoulou Despina, Tsutsui Miho, Padovani Alessandro, Sawcer Stephen J, Hodges John R, Spillantini Maria Grazia
Abstract excerpt
BACKGROUND: The frontotemporal dementia (FTD) syndromes have been associated with the microtubule-associated tau protein since tau gene mutations have been demonstrated to be the cause of FTD and parkinsonism linked to chromosome 17. In cases of FTD without tau gene mutations, however, it is unclear whether genetic variability in the tau gene is associated with the development or modulation of FTD. OBJECTIVE: To...
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