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Article

Does the mitochondrial genome play a role in the etiology of Alzheimer's disease?

Human genetics - 1 Apr 2006

Elson Joanna L, Herrnstadt Corinna, Preston Gwen, Thal Leon, Morris Christopher M, Edwardson J A, Beal M Flint, Turnbull Douglass M, Howell Neil

Abstract excerpt

We report here the analyses of complete mtDNA coding region sequences from more than 270 Alzheimer's disease (AD) patients and normal controls to determine if inherited mtDNA mutations contribute to the etiology of AD. The AD patients and normal individuals were carefully screened and drawn from two populations of European descent in an effort to avoid spurious effects due to local population anomalies. Overall,...

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Identifiers

PMID: 16408223
DOI: 10.1007/s00439-005-0123-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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