Article
Loss of myogenin in postnatal life leads to normal skeletal muscle but reduced body size.
Development (Cambridge, England) - 1 Feb 2006
Knapp Jennifer R, Davie Judith K, Myer Anita, Meadows Eric, Olson Eric N, Klein William H
Abstract excerpt
Although the mechanisms regulating the formation of embryonic skeletal muscle in vertebrates are well characterized, less is known about postnatal muscle formation even though the largest increases in skeletal muscle mass occur after birth. Adult muscle stem cells (satellite cells) appear to recapitulate the events that occur in embryonic myoblasts. In particular, the myogenic basic helix-loop-helix factors,...
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