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Article

Threonine 788 in integrin subunit beta1 regulates integrin activation.

Experimental cell research - 1 Apr 2006

Nilsson Stina, Kaniowska Dorota, Brakebusch Cord, Fässler Reinhard, Johansson Staffan

Abstract excerpt

In the present study, the functional role of suggested phosphorylation of the conserved threonines in the cytoplasmic domain of integrin subunit beta1 was investigated. Mutants mimicking phosphorylated and unphosphorylated forms of beta1 were expressed in beta1 deficient GD25 cells. T788 in beta1 was identified as a site with major influence on integrin function. The mutation to A788 strongly reduced...

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Identifiers

PMID: 16405888
DOI: 10.1016/j.yexcr.2005.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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