Article
[The polymorphism of genes of synthesis and metabolism of estrogens and the risk of breast cancer].
Klinicheskaia laboratornaia diagnostika - 1 Feb 2014
Petchkovskiy E V, Shadrina A S, Boyarskih U A, Selezneva I A, Sinkina T V, Lazarev A F, Petrova V D, Filipenko M L
Abstract excerpt
The genetic polymorphism of enzymes of synthesis and metabolism of estrogens can input into predisposition to breast cancer. The purpose of actual study was to analyze the associations of polymorphic loci CYP17/B1rs10556836, CYP1A 1rs1048943, CYP1A2rs762551, CYP19A1rs2470152 and CYP17A1rs743572 with risk of development of breast cancer in Russian residents of the Western-Siberian region of Russia. The rates of...
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